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What you need

ASIST runs on a Mac and on Windows.

You need a Mac with Apple silicon and macOS 14 or later. ASIST does not run on an Intel Mac.

Speech recognition and the other local models run on your Mac. Speech recognition, and Irodori-TTS and Qwen3-TTS for reading aloud, run on the Mac’s GPU, in programs bundled with the app. With all of them in use, they take about 4.2 GB of memory in total. On a Mac with less than 16 GB of memory, ASIST recommends a smaller model for speech recognition, and they take about 2.8 GB. Choosing Irodori-TTS for reading aloud takes about 2.0 GB more, and Qwen3-TTS about 1.6 GB more. Both are recommended on a Mac with 16 GB of memory or more. The breakdown is in Memory requirements.

You need an API key from one of these providers. You enter it during the first-time setup. Usage is billed to your account with that provider.

Provider Where to create a key
Anthropic console.anthropic.com
OpenAI platform.openai.com
Google aistudio.google.com
Cerebras cloud.cerebras.ai

With a ChatGPT Plus or Pro plan, you can sign in with ChatGPT instead of using an API key. Conversations then count towards your plan’s usage. See Using your ChatGPT plan.

Software What it is for
The codex or claude CLI Agent jobs and memory curation. Install the one you want to use and sign in to it first. See Setting up the Agent.
VOICEVOX or AivisSpeech Reading Japanese aloud. If it is in your Applications folder on a Mac, or installed without changing the install folder on Windows, ASIST starts it in the background and connects to it. One that ASIST started stops when ASIST quits or when you choose another speech engine.

The uv bundled with the app creates the Python environments that searching the memory by meaning, choosing the kind of backchannel and MaAI use. uv also downloads Python at that point, so you do not need to install anything beforehand.

ASIST’s answers can be wrong, the APIs are billed to your own accounts, and an Agent job you approve can change your files. Before you start, read Using ASIST safely.